Reaction Details Report a problem with these data
Target
Dickkopf-related protein 1
Ligand
BDBM50135174
Substrate
n/a
Meas. Tech.
ChEMBL_1545385 (CHEMBL3751610)
IC50
3000±n/a nM
Citation
 Mpousis, S; Thysiadis, S; Avramidis, N; Katsamakas, S; Efthimiopoulos, S; Sarli, V Synthesis and evaluation of gallocyanine dyes as potential agents for the treatment of Alzheimer's disease and related neurodegenerative tauopathies. Eur J Med Chem 108:28-38 (2016) [PubMed]  Article 
Target
Name:
Dickkopf-related protein 1
Synonyms:
DKK1_MOUSE | Dickkopf-1 | Dickkopf-related protein 1 | Dkk-1 | Dkk1 | mDkk-1
Type:
PROTEIN
Mol. Mass.:
29313.46
Organism:
Mus musculus
Description:
ChEMBL_116699
Residue:
272
Sequence:
MMVVCAAAAVRFLAVFTMMALCSLPLLGASATLNSVLINSNAIKNLPPPLGGAGGQPGSAVSVAPGVLYEGGNKYQTLDNYQPYPCAEDEECGSDEYCSSPSRGAAGVGGVQICLACRKRRKRCMRHAMCCPGNYCKNGICMPSDHSHFPRGEIEESIIENLGNDHNAAAGDGYPRRTTLTSKIYHTKGQEGSVCLRSSDCAAGLCCARHFWSKICKPVLKEGQVCTKHKRKGSHGLEIFQRCYCGEGLACRIQKDHHQASNSSRLHTCQRH
  
Inhibitor
Name:
BDBM50135174
Synonyms:
CHEMBL3747431
Type:
Small organic molecule
Emp. Form.:
C15H13ClN2O5
Mol. Mass.:
336.727
SMILES:
Cl.CN(C)c1ccc2nc3c(cc(=O)c(O)c3oc2c1)C(O)=O
Structure:
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