Reaction Details Report a problem with these data
Target
Histone deacetylase 11
Ligand
BDBM50140176
Substrate
n/a
Meas. Tech.
ChEMBL_1547668 (CHEMBL3755719)
IC50
5530±n/a nM
Citation
 Ai, T; Qiu, L; Xie, J; Geraghty, RJ; Chen, L Design and synthesis of an activity-based protein profiling probe derived from cinnamic hydroxamic acid. Bioorg Med Chem 24:686-92 (2016) [PubMed]  Article 
Target
Name:
Histone deacetylase 11
Synonyms:
HD11 | HDA11_HUMAN | HDAC11 | Human HDAC11
Type:
Chromatin regulator; hydrolase; repressor
Mol. Mass.:
39187.66
Organism:
Homo sapiens (Human)
Description:
Q96DB2
Residue:
347
Sequence:
MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
  
Inhibitor
Name:
BDBM50140176
Synonyms:
CHEMBL3394285
Type:
Small organic molecule
Emp. Form.:
C10H8F3NO2
Mol. Mass.:
231.1712
SMILES:
ONC(=O)\C=C\c1ccc(cc1)C(F)(F)F
Structure:
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