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Target
Matrilysin
Ligand
BDBM50140176
Substrate
n/a
Meas. Tech.
ChEMBL_1547673 (CHEMBL3755724)
IC50
>100000±n/a nM
Citation
 Ai, T; Qiu, L; Xie, J; Geraghty, RJ; Chen, L Design and synthesis of an activity-based protein profiling probe derived from cinnamic hydroxamic acid. Bioorg Med Chem 24:686-92 (2016) [PubMed]  Article 
Target
Name:
Matrilysin
Synonyms:
MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1
Type:
Enzyme
Mol. Mass.:
29681.54
Organism:
Homo sapiens (Human)
Description:
P09237
Residue:
267
Sequence:
MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
  
Inhibitor
Name:
BDBM50140176
Synonyms:
CHEMBL3394285
Type:
Small organic molecule
Emp. Form.:
C10H8F3NO2
Mol. Mass.:
231.1712
SMILES:
ONC(=O)\C=C\c1ccc(cc1)C(F)(F)F
Structure:
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