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Target
Neuraminidase
Ligand
BDBM50143053
Substrate
n/a
Meas. Tech.
ChEMBL_1550568 (CHEMBL3762263)
IC50
67200±n/a nM
Citation
 Chen, BL; Wang, YJ; Guo, H; Zeng, GY Design, synthesis, and biological evaluation of crenatoside analogues as novel influenza neuraminidase inhibitors. Eur J Med Chem 109:199-205 (2016) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I33A0
Type:
PROTEIN
Mol. Mass.:
49687.56
Organism:
Influenza A virus
Description:
ChEMBL_1347422
Residue:
453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVAGQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWDPNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETIWTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
  
Inhibitor
Name:
BDBM50143053
Synonyms:
CHEMBL3759493
Type:
Small organic molecule
Emp. Form.:
C23H24O9
Mol. Mass.:
444.4313
SMILES:
[H][C@]12OC[C@@H](O[C@]1([H])[C@@H](OC(=O)\C=C\c1ccc(O)c(O)c1)[C@H](O)[C@@H](CO)O2)c1ccccc1 |r|
Structure:
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