Reaction Details Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM50152968
Substrate
n/a
Meas. Tech.
ChEMBL_1554922 (CHEMBL3767074)
Ki
20000±n/a nM
Citation
 Vullo, D; Del Prete, S; De Luca, V; Carginale, V; Ferraroni, M; Dedeoglu, N; Osman, SM; AlOthman, Z; Capasso, C; Supuran, CT Anion inhibition studies of the฿-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. Bioorg Med Chem Lett 26:1406-10 (2016) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50152968
Synonyms:
Blausaeure | CHEMBL183419 | Cyanwasserstoff | [CHN] | formonitrile | hydridonitridocarbonhydrogen(nitridocarbonate)methanenitrile | hydrocyanic acid | hydrogen cyanide
Type:
Small organic molecule
Emp. Form.:
CHN
Mol. Mass.:
27.0253
SMILES:
C#N
Structure:
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