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TargetCalcitonin gene-related peptide (CGRP alpha)
LigandBDBM50150448
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1558562
IC50 460±n/a nM
Citation Civiello, RLHan, XBeno, BRChaturvedula, PVHerbst, JJXu, CConway, CMMacor, JEDubowchik, GM Synthesis and SAR of calcitonin gene-related peptide (CGRP) antagonists containing substituted aryl-piperazines and piperidines. Bioorg Med Chem Lett26:1229-32 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Calcitonin gene-related peptide (CGRP alpha)
Name:Calcitonin gene-related peptide (CGRP alpha)
Synonyms:CGRP | Calcitonin gene-related peptide 1
Type:Enzyme
Mol. Mass.:13902.80
Organism:Homo sapiens (Human)
Description:P06881
Residue:128
Sequence:
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQNYVQ
MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG
RRRRDLQA
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BDBM50150448
NameBDBM50150448
Synonyms:CHEMBL3769822
TypeSmall organic molecule
Emp. Form.C33H44N6O2
Mol. Mass.556.7415
SMILESCc1cc(C[C@@H](NC(=O)N2CCC(CC2)c2ccccc2)C(=O)N2CCC(CC2)N2CCCCC2)cc2cn[nH]c12 |r|
Structure
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