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Target
Calcitonin gene-related peptide 1
Ligand
BDBM50150460
Substrate
n/a
Meas. Tech.
ChEMBL_1558562 (CHEMBL3773899)
IC50
44±n/a nM
Citation
 Civiello, RL; Han, X; Beno, BR; Chaturvedula, PV; Herbst, JJ; Xu, C; Conway, CM; Macor, JE; Dubowchik, GM Synthesis and SAR of calcitonin gene-related peptide (CGRP) antagonists containing substituted aryl-piperazines and piperidines. Bioorg Med Chem Lett 26:1229-32 (2016) [PubMed]  Article 
Target
Name:
Calcitonin gene-related peptide 1
Synonyms:
CALC1 | CALCA | CALCA_HUMAN | CGRP | Calcitonin gene-related peptide (CGRP alpha) | Calcitonin gene-related peptide 1
Type:
Enzyme
Mol. Mass.:
13902.80
Organism:
Homo sapiens (Human)
Description:
P06881
Residue:
128
Sequence:
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFGRRRRDLQA
  
Inhibitor
Name:
BDBM50150460
Synonyms:
CHEMBL3770927
Type:
Small organic molecule
Emp. Form.:
C35H47N7O4
Mol. Mass.:
629.7922
SMILES:
CCOC(=O)c1ccc(cc1)N1CCN(CC1)C(=O)N[C@H](Cc1cc(C)c2[nH]ncc2c1)C(=O)N1CCC(CC1)N1CCCCC1 |r|
Structure:
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