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Target
Kallikrein-2
Ligand
BDBM50292533
Substrate
n/a
Meas. Tech.
ChEMBL_1558619 (CHEMBL3774272)
IC50
3200±n/a nM
Citation
 Santos, JA; Kondo, MY; Freitas, RF; dos Santos, MH; Ramalho, TC; Assis, DM; Juliano, L; Juliano, MA; Puzer, L The natural flavone fukugetin as a mixed-type inhibitor for human tissue kallikreins. Bioorg Med Chem Lett 26:1485-9 (2016) [PubMed]  Article 
Target
Name:
Kallikrein-2
Synonyms:
Glandular kallikrein-1 | KLK2 | KLK2_HUMAN | Kallikrein 2 | Kallikrein-2 | Tissue kallikrein-2 | hGK-1
Type:
PROTEIN
Mol. Mass.:
28673.68
Organism:
Homo sapiens (Human)
Description:
ChEMBL_862797
Residue:
261
Sequence:
MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP
  
Inhibitor
Name:
BDBM50292533
Synonyms:
CHEMBL446790 | Fukugetin
Type:
Small organic molecule
Emp. Form.:
C30H22O11
Mol. Mass.:
558.4891
SMILES:
Oc1ccc(cc1)[C@@H]1Oc2cc(O)cc(O)c2C(=O)[C@H]1c1c(O)cc(O)c2C(=O)CC(Oc12)c1ccc(O)c(O)c1 |r|
Structure:
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