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Reaction Details
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TargetMelatonin receptor
LigandBDBM50114703
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1560584
Ki 0.020000±n/a nM
Citation Dosa, PIAmin, EA Tactical Approaches to Interconverting GPCR Agonists and Antagonists. J Med Chem59:810-40 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1B | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:Enzyme
Mol. Mass.:40203.54
Organism:Homo sapiens (Human)
Description:P49286
Residue:362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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  Blast E-value cutoff:
BDBM50114703
NameBDBM50114703
Synonyms:CHEMBL287560 | N-[2-(5-Methoxy-2-phenyl-benzofuran-3-yl)-ethyl]-acetamide
TypeSmall organic molecule
Emp. Form.C19H19NO3
Mol. Mass.309.3591
SMILESCOc1ccc2oc(c(CCNC(C)=O)c2c1)-c1ccccc1
Structure
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n/a