Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50114703
Substrate
n/a
Meas. Tech.
ChEMBL_1560583 (CHEMBL3777315)
Ki
0.010000±n/a nM
Citation
 Dosa, PI; Amin, EA Tactical Approaches to Interconverting GPCR Agonists and Antagonists. J Med Chem 59:810-40 (2016) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50114703
Synonyms:
CHEMBL287560 | N-[2-(5-Methoxy-2-phenyl-benzofuran-3-yl)-ethyl]-acetamide
Type:
Small organic molecule
Emp. Form.:
C19H19NO3
Mol. Mass.:
309.3591
SMILES:
COc1ccc2oc(c(CCNC(C)=O)c2c1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: