Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50152102
Substrate
n/a
Meas. Tech.
ChEMBL_1565146 (CHEMBL3782504)
Ki
69±n/a nM
Citation
 Deiana, V; Gómez-Cañas, M; Pazos, MR; Fernández-Ruiz, J; Asproni, B; Cichero, E; Fossa, P; Muñoz, E; Deligia, F; Murineddu, G; García-Arencibia, M; Pinna, GA Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties. Eur J Med Chem 112:66-80 (2016) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50152102
Synonyms:
CHEMBL3781781
Type:
Small organic molecule
Emp. Form.:
C25H24Cl2N4O
Mol. Mass.:
467.39
SMILES:
Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCCC2)c2Cc3cc(ccc3-c12)C1CC1
Structure:
Search PDB for entries with ligand similarity: