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TargetMelatonin receptor 1B
LigandBDBM81767
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1559800
IC50 7.4±n/a nM
Citation Waszkielewicz, AMGunia-Krzyzak, APowroznik, BSloczynska, KPekala, EWalczak, MBednarski, MZeslawska, ENitek, WMarona, H Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents. Bioorg Med Chem24:1793-810 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor 1B
Name:Melatonin receptor 1B
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:40205.08
Organism:Rattus norvegicus
Description:ChEMBL_104938
Residue:364
Sequence:
MPDNSSIANCCAASGLAARPSWPGSAEAEPPETPRAPWVAPMLSTVVIVTTAVDFVGNLL
VILSVLRNRKLRNAGNLFVVNLALADLVVALYPYPLILVAILHDGWVLGEIHCKASAFVM
GLSVIGSVFNITAIAINRYWCICHSATYHRACSQWHAPLYISLIWLLTLVALVPNFFVGS
LEYDPRIYSCTFIQTASTQYTMAVVAIHFLLPIAVVSFCYLRIWILVLQARRKAKAERKL
RLRPSDLRSFLTMFAVFVVFAICWAPLNCIGLAVAINPEAMALQIPEGLFVTSYFLAYFN
SCLNAIVYGLLNQNFRREYKRILSALWSTGRCFHDASKCHLTEDLQGPVPPAAMATIPVQ
EGAL
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BDBM81767
NameBDBM81767
Synonyms:15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646 | Somatostatin-14
TypeSmall organic molecule
Emp. Form.C76H104N18O19S2
Mol. Mass.1637.878
SMILESC[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r|
Structure
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n/a