Reaction Details Report a problem with these data
Target
Glutathione S-transferase omega-1
Ligand
BDBM50155925
Substrate
n/a
Meas. Tech.
ChEMBL_1564782 (CHEMBL3784289)
IC50
250±n/a nM
Citation
 Baldwin, AG; Brough, D; Freeman, S Inhibiting the Inflammasome: A Chemical Perspective. J Med Chem 59:1691-710 (2016) [PubMed]  Article 
Target
Name:
Glutathione S-transferase omega-1
Synonyms:
GSTO 1-1 | GSTO1 | GSTO1_HUMAN | GSTTLP28 | Glutathione S-transferase omega-1 | Glutathione transferase omega 1 | glutathione S-transferase omega-1 isoform 1
Type:
PROTEIN
Mol. Mass.:
27565.54
Organism:
Homo sapiens (Human)
Description:
EBI_11172
Residue:
241
Sequence:
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
  
Inhibitor
Name:
BDBM50155925
Synonyms:
CHEMBL3781794
Type:
Small organic molecule
Emp. Form.:
C21H21FN2O4S
Mol. Mass.:
416.466
SMILES:
Fc1ccc(cc1S(=O)(=O)NC(=O)Nc1c2CCCc2cc2CCCc12)C1CO1
Structure:
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