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Target
Thyrotropin-releasing hormone receptor
Ligand
BDBM50158397
Substrate
n/a
Meas. Tech.
ChEMBL_1564320 (CHEMBL3784641)
IC50
>50000±n/a nM
Citation
 Meena, CL; Thakur, A; Nandekar, PP; Sharma, SS; Sangamwar, AT; Jain, R Synthesis and biology of ring-modified l-Histidine containing thyrotropin-releasing hormone (TRH) analogues. Eur J Med Chem 111:72-83 (2016) [PubMed]  Article 
Target
Name:
Thyrotropin-releasing hormone receptor
Synonyms:
TRH-R2 | Thyrotropin-releasing hormone receptor 2
Type:
PROTEIN
Mol. Mass.:
27545.04
Organism:
Mus musculus
Description:
ChEMBL_109850
Residue:
251
Sequence:
MDGPSNVSLVHGDTTLGLPEYKVVSVLLVLLVCTVGIVGNAMVVLVVLTSRDMHTPTNCYLVSLALADLIVLLAAGLPNVSDSLVGHWIYGHAGCLGITYFQYLGINVSSCSILAFTVERYIAICHPMRAQTVCTVARARRIIAGIWGVTSLYCLLWFFLVDLNVRDNQRLECGYKVSRGLYLPIYLLDFAVFFIAPLLGTLVLYGFIGRILFQSPLSQEAWQKERQSHGQSEGTPGNCSRSKSSMSSRKQ
  
Inhibitor
Name:
BDBM50158397
Synonyms:
CHEMBL3780836
Type:
Small organic molecule
Emp. Form.:
C16H20Cl2N6O4
Mol. Mass.:
431.274
SMILES:
NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1nc(Cl)[nH]c1Cl)NC(=O)[C@@H]1CCC(=O)N1 |r|
Structure:
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