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Target
Carbonic anhydrase
Ligand
BDBM50158530
Substrate
n/a
Meas. Tech.
ChEMBL_1566138 (CHEMBL3787807)
Ki
88±n/a nM
Citation
 Akdemir, A; Güzel-Akdemir, Ö; Karali, N; Supuran, CT Isatin analogs as novel inhibitors of Candida spp.ß-carbonic anhydrase enzymes. Bioorg Med Chem 24:1648-52 (2016) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
CAN_CANAL | NCE103 | beta-Carbonic Anhydrase
Type:
Enzyme
Mol. Mass.:
31587.59
Organism:
Candida albicans (Yeast)
Description:
n/a
Residue:
281
Sequence:
MGRENILKYQLEHDHESDLVTEKDQSLLLDNNNNLNGMNNTIKTHPVRVSSGNHNNFPFTLSSESTLQDFLNNNKFFVDSIKHNHGNQIFDLNGQGQSPHTLWIGCSDSRAGDQCLATLPGEIFVHRNIANIVNANDISSQGVIQFAIDVLKVKKIIVCGHTDCGGIWASLSKKKIGGVLDLWLNPVRHIRAANLKLLEEYNQDPKLKAKKLAELNVISSVTALKRHPSASVALKKNEIEVWGMLYDVATGYLSQVEIPQDEFEDLFHVHDEHDEEEYNPH
  
Inhibitor
Name:
BDBM50158530
Synonyms:
CHEMBL3786477
Type:
Small organic molecule
Emp. Form.:
C15H10F3N3O4S
Mol. Mass.:
385.318
SMILES:
NS(=O)(=O)c1cccc(c1)\N=C1/C(=O)Nc2ccc(OC(F)(F)F)cc12
Structure:
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