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Target
Carbonic anhydrase
Ligand
BDBM50147211
Substrate
n/a
Meas. Tech.
ChEMBL_1566138 (CHEMBL3787807)
Ki
34±n/a nM
Citation
 Akdemir, A; Güzel-Akdemir, Ö; Karali, N; Supuran, CT Isatin analogs as novel inhibitors of Candida spp.ß-carbonic anhydrase enzymes. Bioorg Med Chem 24:1648-52 (2016) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
CAN_CANAL | NCE103 | beta-Carbonic Anhydrase
Type:
Enzyme
Mol. Mass.:
31587.59
Organism:
Candida albicans (Yeast)
Description:
n/a
Residue:
281
Sequence:
MGRENILKYQLEHDHESDLVTEKDQSLLLDNNNNLNGMNNTIKTHPVRVSSGNHNNFPFTLSSESTLQDFLNNNKFFVDSIKHNHGNQIFDLNGQGQSPHTLWIGCSDSRAGDQCLATLPGEIFVHRNIANIVNANDISSQGVIQFAIDVLKVKKIIVCGHTDCGGIWASLSKKKIGGVLDLWLNPVRHIRAANLKLLEEYNQDPKLKAKKLAELNVISSVTALKRHPSASVALKKNEIEVWGMLYDVATGYLSQVEIPQDEFEDLFHVHDEHDEEEYNPH
  
Inhibitor
Name:
BDBM50147211
Synonyms:
CHEMBL3765353
Type:
Small organic molecule
Emp. Form.:
C14H10N4O5S
Mol. Mass.:
346.318
SMILES:
NS(=O)(=O)c1ccc(cc1)\N=C1/C(=O)Nc2ccc(cc12)[N+]([O-])=O
Structure:
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