Reaction Details Report a problem with these data
Target
Integrase
Ligand
BDBM50163753
Substrate
n/a
Meas. Tech.
ChEMBL_1576407 (CHEMBL3802836)
Kd
2800000±n/a nM
Citation
 Zhan, P; Pannecouque, C; De Clercq, E; Liu, X Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends. J Med Chem 59:2849-78 (2016) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
pol
Type:
PROTEIN
Mol. Mass.:
32203.43
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_106649
Residue:
288
Sequence:
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50163753
Synonyms:
CHEMBL1615094
Type:
Small organic molecule
Emp. Form.:
C8H9N3S
Mol. Mass.:
179.242
SMILES:
Cn1nc(cc1N)-c1cccs1
Structure:
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