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TargetCaveolin-1
LigandBDBM50172458
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1579921
Kd>155±n/a nM
Citation Gilliam, AJSmith, JNFlather, DJohnston, KMGansmiller, AMFishman, DAEdgar, JMBalk, MMajumdar, SWeiss, GA Affinity-Guided Design of Caveolin-1 Ligands for Deoligomerization. J Med Chem59:4019-25 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Caveolin-1
Name:Caveolin-1
Synonyms:CAV | CAV1 | Caveolin-1
Type:PROTEIN
Mol. Mass.:20469.35
Organism:Homo sapiens (Human)
Description:ChEMBL_116797
Residue:178
Sequence:
MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLN
DDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFA
ILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50172458
NameBDBM50172458
Synonyms:CHEMBL3809899
TypeSmall organic molecule
Emp. Form.C191H302N50O62S3
Mol. Mass.4386.934
SMILESCC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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