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Target
Synapsin-1
Ligand
BDBM50180856
Substrate
n/a
Meas. Tech.
ChEMBL_1584964 (CHEMBL3819988)
IC50
500±n/a nM
Citation
 Ehrt, C; Brinkjost, T; Koch, O Impact of Binding Site Comparisons on Medicinal Chemistry and Rational Molecular Design. J Med Chem 59:4121-51 (2016) [PubMed]  Article 
Target
Name:
Synapsin-1
Synonyms:
SYN1 | SYN1_BOVIN | Synapsin I | Synapsin-1
Type:
PROTEIN
Mol. Mass.:
74549.40
Organism:
Bos taurus
Description:
ChEMBL_116805
Residue:
706
Sequence:
MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPAAPSPGATTGPATATAERASSAAPVASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSINSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLINQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATTEPFIDAKYDVRIQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIQVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHSQTPSPGALPLGRQISQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPTPQGQQHLSGLGPPAGSPLPQRLPSPTSVPQQPASQATPMTQGQGRQSRPVAGGPGAPPATRPPASPSPQRQAGPPQATRQTSVSGQAPPKASGVPPGGQQRQGPPQKPPGPAGPTRQASQAGPMPRTGPPTTQQPRPSGPGPAGRPTKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD
  
Inhibitor
Name:
BDBM50180856
Synonyms:
CHEMBL3818384
Type:
Small organic molecule
Emp. Form.:
C10H3I4NO4
Mol. Mass.:
708.753
SMILES:
OC(=O)CN1C(=O)c2c(C1=O)c(I)c(I)c(I)c2I
Structure:
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