Reaction Details Report a problem with these data
Target
Inosine-adenosine-guanosine-nucleoside hydrolase
Ligand
BDBM50187701
Substrate
n/a
Meas. Tech.
ChEMBL_1589255 (CHEMBL3830283)
Ki
3.0±n/a nM
Citation
 Wróblewski, AE; Glowacka, IE; Piotrowska, DG 1'-Homonucleosides and their structural analogues: A review. Eur J Med Chem 118:121-42 (2016) [PubMed]  Article 
Target
Name:
Inosine-adenosine-guanosine-nucleoside hydrolase
Synonyms:
Inosine-adenosine-guanosine-nucleoside hydrolase
Type:
PROTEIN
Mol. Mass.:
35861.89
Organism:
Trypanosoma brucei brucei
Description:
ChEMBL_116820
Residue:
327
Sequence:
MAKTVILDHDGNKDDFVAMILLLSNPKKVNLIGCICTDADCFVENGFDVTGKIMCAMHRLTKTPLFPIGKSTATAVNAFPTEWRFSAKNLDDMPFLNIVEDVALWEKLKPENEAHNGQQLLADLVMKSKEKVTVCVTGPLSNMAWCIEKYGEAFTSKVEECVIMGGAVDVGGNVFLPTTDGSAEWNIYWDPPAAKKVLCCPNIRCVLFSLDATNTVPVRSVDVKGFGAQNQYLLSQMVGTMWAMSTHEEILRDGDAYYAWDALTAAYILEPTIATLEPVALDVDVSKGKSEGRTPRASGEGKPCAHVARNPSKQMFHDLVFASTRVY
  
Inhibitor
Name:
BDBM50187701
Synonyms:
CHEMBL3827395
Type:
Small organic molecule
Emp. Form.:
C11H15N5O3
Mol. Mass.:
265.2685
SMILES:
Nc1ncnc2C(C=Nc12)[C@@H]1N[C@H](CO)[C@@H](O)[C@H]1O |r,c:7|
Structure:
Search PDB for entries with ligand similarity: