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TargetInosine-uridine preferring nucleoside hydrolase
LigandBDBM50187702
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1589257
Ki 5400±n/a nM
Citation Wróblewski, AEGlowacka, IEPiotrowska, DG 1'-Homonucleosides and their structural analogues: A review. Eur J Med Chem118:121-42 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Inosine-uridine preferring nucleoside hydrolase
Name:Inosine-uridine preferring nucleoside hydrolase
Synonyms:IU-NH | IU-nucleoside hydrolase | IUNH | Inosine-uridine preferring nucleoside hydrolase | Non-specific nucleoside hydrolase | Purine nucleosidase
Type:PROTEIN
Mol. Mass.:34318.86
Organism:Crithidia fasciculata
Description:ChEMBL_116821
Residue:315
Sequence:
MPKKIILDCDPGLDDAVAILLAHGNPEIELLAITTVVGNQTLAKVTRNAQLVADIAGITG
VPIAAGCDKPLVRKIMTAGHIHGESGMGTVAYPAEFKNKVDERHAVNLIIDLVMSHEPKT
ITLVPTGGLTNIAMAARLEPRIVDRVKEVVLMGGGYHEGNATSVAEFNIIIDPEAAHIVF
NESWQVTMVGLDLTHQALATPPILQRVKEVDTNPARFMLEIMDYYTKIYQSNRYMAAAAV
HDPCAVAYVIDPSVMTTERVPVDIELTGKLTLGMTVADFRNPRPEHCHTQVAVKLDFEKF
WGLVLDALERIGDPQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50187702
NameBDBM50187702
Synonyms:CHEMBL3828258
TypeSmall organic molecule
Emp. Form.C11H16N6O3
Mol. Mass.280.2831
SMILESNc1ncnc2n(C[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)cnc12 |r|
Structure
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n/a