Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetInosine-uridine preferring nucleoside hydrolase
LigandBDBM50187703
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1589257
Ki 5400±n/a nM
Citation Wróblewski, AEGlowacka, IEPiotrowska, DG 1'-Homonucleosides and their structural analogues: A review. Eur J Med Chem118:121-42 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Inosine-uridine preferring nucleoside hydrolase
Name:Inosine-uridine preferring nucleoside hydrolase
Synonyms:IU-NH | IU-nucleoside hydrolase | IUNH | Inosine-uridine preferring nucleoside hydrolase | Non-specific nucleoside hydrolase | Purine nucleosidase
Type:PROTEIN
Mol. Mass.:34318.86
Organism:Crithidia fasciculata
Description:ChEMBL_116821
Residue:315
Sequence:
MPKKIILDCDPGLDDAVAILLAHGNPEIELLAITTVVGNQTLAKVTRNAQLVADIAGITG
VPIAAGCDKPLVRKIMTAGHIHGESGMGTVAYPAEFKNKVDERHAVNLIIDLVMSHEPKT
ITLVPTGGLTNIAMAARLEPRIVDRVKEVVLMGGGYHEGNATSVAEFNIIIDPEAAHIVF
NESWQVTMVGLDLTHQALATPPILQRVKEVDTNPARFMLEIMDYYTKIYQSNRYMAAAAV
HDPCAVAYVIDPSVMTTERVPVDIELTGKLTLGMTVADFRNPRPEHCHTQVAVKLDFEKF
WGLVLDALERIGDPQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50187703
NameBDBM50187703
Synonyms:CHEMBL3827853
TypeSmall organic molecule
Emp. Form.C11H15N5O4
Mol. Mass.281.2679
SMILESOC[C@H]1N[C@@H](Cn2cnc3c(O)ncnc23)[C@H](O)[C@@H]1O |r|
Structure
n/a