Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50189065
Substrate
n/a
Meas. Tech.
ChEMBL_1591031 (CHEMBL3831009)
Ki
>100000±n/a nM
Citation
 Bharate, SB; Singh, B; Kachler, S; Oliveira, A; Kumar, V; Bharate, SS; Vishwakarma, RA; Klotz, KN; Gutiérrez de Terán, H Discovery of 7-(Prolinol-N-yl)-2-phenylamino-thiazolo[5,4-d]pyrimidines as Novel Non-Nucleoside Partial Agonists for the A2A Adenosine Receptor: Prediction from Molecular Modeling. J Med Chem 59:5922-8 (2016) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50189065
Synonyms:
CHEMBL3088350
Type:
Small organic molecule
Emp. Form.:
C13H12ClN5S
Mol. Mass.:
305.786
SMILES:
CN(C)c1ncnc2sc(Nc3ccc(Cl)cc3)nc12
Structure:
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