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Target
Chromobox protein homolog 1
Ligand
BDBM50194259
Substrate
n/a
Meas. Tech.
ChEMBL_1616638 (CHEMBL3858707)
Kd
>100000±n/a nM
Citation
 Stuckey, JI; Simpson, C; Norris-Drouin, JL; Cholensky, SH; Lee, J; Pasca, R; Cheng, N; Dickson, BM; Pearce, KH; Frye, SV; James, LI Structure-Activity Relationships and Kinetic Studies of Peptidic Antagonists of CBX Chromodomains. J Med Chem 59:8913-8923 (2016) [PubMed]  Article 
Target
Name:
Chromobox protein homolog 1
Synonyms:
CBX | CBX1 | CBX1_HUMAN | HP1 beta | HP1Hsbeta | Heterochromatin protein 1 homolog beta | Heterochromatin protein p25 | M31 | Modifier 1 protein | p25beta
Type:
PROTEIN
Mol. Mass.:
21405.43
Organism:
Homo sapiens (Human)
Description:
ChEMBL_103989
Residue:
185
Sequence:
MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN
  
Inhibitor
Name:
BDBM50194259
Synonyms:
CHEMBL3939958
Type:
Small organic molecule
Emp. Form.:
C43H66N6O8
Mol. Mass.:
795.0195
SMILES:
CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Structure:
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