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Target
Melanocortin receptor 4
Ligand
BDBM50201670
Substrate
n/a
Meas. Tech.
ChEMBL_1623252 (CHEMBL3865604)
EC50
20000±n/a nM
Citation
 Agarwal, S; Sasane, S; Deshmukh, P; Rami, B; Bandyopadhyay, D; Giri, P; Giri, S; Jain, M; Desai, RC Identification of an Orally Efficacious GPR40/FFAR1 Receptor Agonist. ACS Med Chem Lett 7:1134-1138 (2016) [PubMed]  Article 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R_RAT | Mc4r
Type:
PROTEIN
Mol. Mass.:
36892.87
Organism:
Rattus norvegicus
Description:
ChEMBL_11005
Residue:
332
Sequence:
MNSTHHHGMYTSLHLWNRSSHGLHGNASESLGKGHSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLITMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGANMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYPLGGICELPGRY
  
Inhibitor
Name:
BDBM50201670
Synonyms:
CHEMBL3930086
Type:
Small organic molecule
Emp. Form.:
C56H60CaN2O6S2
Mol. Mass.:
961.293
SMILES:
[Ca++].CC#C[C@@H](CC([O-])=O)c1ccc(OCc2cccc(CN(Cc3ccsc3)C(C)C)c2)cc1.CC#C[C@@H](CC([O-])=O)c1ccc(OCc2cccc(CN(Cc3ccsc3)C(C)C)c2)cc1 |r|
Structure:
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