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Target
Beta-galactosidase
Ligand
BDBM50204211
Substrate
n/a
Meas. Tech.
ChEMBL_1626901 (CHEMBL3869422)
IC50
414000±n/a nM
Citation
 Miyawaki, S; Hirokami, Y; Kinami, K; Hoshino, M; Minehira, D; Miyamoto, D; Nash, RJ; Fleet, GW; Adachi, I; Toyooka, N; Kato, A Strategy for designing selectivea-l-rhamnosidase inhibitors: Synthesis and biological evaluation of l-DMDP cyclic isothioureas. Bioorg Med Chem 25:107-115 (2017) [PubMed]  Article 
Target
Name:
Beta-galactosidase
Synonyms:
β-galactosidase | BGAL_BOVIN | Beta-galactosidase/Glucosylceramidase | GLB1
Type:
Protein
Mol. Mass.:
73420.88
Organism:
Bos taurus (Bovine)
Description:
n/a
Residue:
653
Sequence:
MPGVVRLLALLLVPLLLGSARGLHNATQRTFQIDYRRNRFLKDGQPFRYISGSIHYFRVPRFYWKDRLLKMKMAGLNAIQTYVAWNFHELQPGRYNFSGDHDVEHFIQLAHELGLLVILRPGPYICAEWDMGGLPAWLLEKKSIVLRSSDPDYLAAVDKWLGVLLPKMRPLLYKNGGPIITVQVENEYGSYLSCDYDYLRFLQKRFHDHLGEDVLLFTTDGVNERLLQCGALQGLYATVDFSPGTNLTAAFMLQRKFEPTGPLVNSEFYTGWLDHWGQRHSTVSSKAVAFTLHDMLALGANVNMYMFIGGTNFAYWNGANIPYQPQPTSYDYDAPLSEAGDLTEKYFALRDIIQKFAKVPEGPIPPSTPKFAYGKVALNKLKTVEDALNILCPSGPIKSVYPLTFIDVKQYFGFVLYRTMLPEDCSDPTPLSSPLSGVHDRAYVSVNGVAQGILERESVITLNITGKAGATLDLLVENMGRVNYGSSINDFKGLVSNLTLGSKILTNWEIFPLDMEDAVRSHLGTWGGRDRGYHNKARAHSPPTYALPTFYVGNFTIPSGIADLPQDTFIQFPGWTKGQVWINGFNLGRYWPVRGPQMTLFVPQHILVTSTPNTIVVLELEHAPCQDGGPELCTVEFVDKPVFRTVQTHRHAN
  
Inhibitor
Name:
BDBM50204211
Synonyms:
CHEMBL3944457
Type:
Small organic molecule
Emp. Form.:
C15H30N2O4S
Mol. Mass.:
334.475
SMILES:
CCCCCCCCNC(=S)N1[C@H](CO)[C@@H](O)[C@H](O)[C@H]1CO |r|
Structure:
Search PDB for entries with ligand similarity: