Target
Macrophage migration inhibitory factor
Ligand
BDBM50167985
Substrate
n/a
Meas. Tech.
ChEMBL_1628621 (CHEMBL3871206)
Ki
161±n/a nM
Citation
 Cisneros, JARobertson, MJMercado, BQJorgensen, WL Systematic Study of Effects of Structural Modifications on the Aqueous Solubility of Drug-like Molecules. ACS Med Chem Lett 8:124-127 (2017) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
  
Inhibitor
Name:
BDBM50167985
Synonyms:
CHEMBL3798384 | US10336721, Example 21 | US10968198, Example 21
Type:
Small organic molecule
Emp. Form.:
C25H27N5O4
Mol. Mass.:
461.513
SMILES:
Oc1ccc(cc1)-n1cc(nn1)-c1ccc2cc(OCCOCCN3CCOCC3)ccc2n1
Structure:
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