Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50210819
Substrate
n/a
Meas. Tech.
ChEMBL_1635279 (CHEMBL3878177)
Ki
30±n/a nM
Citation
 Alachouzos, G; Lenselink, EB; Mulder-Krieger, T; de Vries, H; IJzerman, AP; Louvel, J Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A Eur J Med Chem 125:586-602 (2017) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50210819
Synonyms:
CHEMBL3916959
Type:
Small organic molecule
Emp. Form.:
C17H14ClN3O
Mol. Mass.:
311.766
SMILES:
COc1ccc(cc1Cl)-c1cnc(N)nc1-c1ccccc1
Structure:
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