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Target
Platelet glycoprotein VI
Ligand
BDBM50211284
Substrate
n/a
Meas. Tech.
ChEMBL_1636302 (CHEMBL3879200)
IC50
6700±n/a nM
Citation
 Bhunia, SS; Misra, A; Khan, IA; Gaur, S; Jain, M; Singh, S; Saxena, A; Hohlfield, T; Dikshit, M; Saxena, AK Novel Glycoprotein VI Antagonists as Antithrombotics: Synthesis, Biological Evaluation, and Molecular Modeling Studies on 2,3-Disubstituted Tetrahydropyrido(3,4-b)indoles. J Med Chem 60:322-337 (2017) [PubMed]  Article 
Target
Name:
Platelet glycoprotein VI
Synonyms:
GP6 | GPVI | GPVI_HUMAN | Glycoprotein 6 | Platelet glycoprotein VI
Type:
PROTEIN
Mol. Mass.:
36878.67
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109099
Residue:
339
Sequence:
MSPSPTALFCLGLCLGRVPAQSGPLPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLEKLSSSRYQDQAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQCQTRYGFDQFALYKEGDPAPYKNPERWYRASFPIITVTAAHSGTYRCYSFSSRDPYLWSAPSDPLELVVTGTSVTPSRLPTEPPSPVAEFSEATAELTVSFTNEVFTTETSRSITASPKESDSPAGPARQYYTKGNLVRICLGAVILIILAGFLAEDWHSRRKRLRHRGRAVQRPLPPLPPLPLTRKSNGGQDGGRQDVHSRGLCS
  
Inhibitor
Name:
BDBM50211284
Synonyms:
CHEMBL3959435
Type:
Small organic molecule
Emp. Form.:
C19H19N3O4S
Mol. Mass.:
385.437
SMILES:
COc1ccc(cc1)S(=O)(=O)N1Cc2[nH]c3ccccc3c2CC1C(N)=O
Structure:
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