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Target
Carbonic anhydrase 6
Ligand
BDBM50212308
Substrate
n/a
Meas. Tech.
ChEMBL_47172 (CHEMBL883496)
IC50
5.0±n/a nM
Citation
  TBA Bioorg Med Chem Lett 1:407-410 (1991)   
Target
Name:
Carbonic anhydrase 6
Synonyms:
CA-VI | CA6 | CAH6_BOVIN | Carbonate dehydratase VI | Carbonic anhydrase 6 | Carbonic anhydrase VI | Salivary carbonic anhydrase | Secreted carbonic anhydrase
Type:
PROTEIN
Mol. Mass.:
37008.14
Organism:
Bos taurus
Description:
ChEMBL_104851
Residue:
319
Sequence:
MITLLFLLVVGAQAQHEWTYSEGVLDEKHWRLQYPDCGGTRQSPIDLKMKKVRYNPSLRALNLTGYGLRQGEFPMTNNGHTVQISLPSSMRMTTSDGSQYLAKQMHFHWGGDSSEISGSEHTVDGMRYIIEIHVVHYHSKYGSYEEAQNEPDGLAVLAALVEVKDYAENTYYSNFISHLEDIRYAGQSTVLRDLDIQDMLPGDLRYYYSYLGSLTTPSCTENVHWFVVADTVKLSKTQIEKLENSLLNHQNETIQNNYRSTQPLNHRVVEANFVSHPHQEYTLGSKLHFYLNNIDQNLEYLRRFIEQKITKRKKEKYWP
  
Inhibitor
Name:
BDBM50212308
Synonyms:
CHEMBL130950
Type:
Small organic molecule
Emp. Form.:
C19H19N5O5S2
Mol. Mass.:
461.515
SMILES:
NS(=O)(=O)c1nnc(NC(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)s1
Structure:
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