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TargetAngiotensin II receptor
LigandBDBM50005347
Substrate/Competitorn/a
Meas. Tech.ChEMBL_36176
IC50 2300±n/a nM
Citation  TBA Bioorg Med Chem Lett3:1019-1024 (1993)  
More Info.:Get all data from this article,  Assay Method
 
Angiotensin II receptor
Name:Angiotensin II receptor
Synonyms:n/a
Type:n/a
Mol. Mass.:n/a
Description:ASSAY_ID of ChEMBL is 357784
Components:This complex has 2 components.
Component 1
Name:Angiotensin II receptor
Synonyms:AT1 | AT1AR | AT1BR | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1)
Type:Protein
Mol. Mass.:41080.75
Organism:Homo sapiens (Human)
Description:P30556
Residue:359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
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Component 2
Name:Angiotensin II receptor
Synonyms:AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Angiotensin II, central | Type-2 angiotensin II receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:41201.61
Organism:Homo sapiens (Human)
Description:Angiotensin II, central 0 0::P50052
Residue:363
Sequence:
MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL
VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET
FVS
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BDBM50005347
NameBDBM50005347
Synonyms:4'-((2-butyl-1H-benzo[d]imidazol-1-yl)methyl)biphenyl-2-carboxylic acid | 4'-(2-Butyl-benzoimidazol-1-ylmethyl)-biphenyl-2-carboxylic acid | 4'-(2-Butyl-benzoimidazol-1-ylmethyl)-biphenyl-2-carboxylic acid;0.25H2O | CHEMBL7632
TypeSmall organic molecule
Emp. Form.C25H24N2O2
Mol. Mass.384.4703
SMILESCCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Structure
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n/a