Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50215153
Substrate
n/a
Meas. Tech.
ChEMBL_211480 (CHEMBL819683)
IC50
3000±n/a nM
Citation
 Ohsumi, K; Hatanaka, T; Fujita, K; Nakagawa, R; Fukuda, Y; Nihei, Y; Suga, Y; Morinaga, Y; Akiyama, Y; Tsuji, T Syntheses and antitumor activity of cis-restricted combretastatins: 5-membered heterocyclic analogues. Bioorg Med Chem Lett 8:3153-8 (1998) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50215153
Synonyms:
CHEMBL108621
Type:
Small organic molecule
Emp. Form.:
C19H21N3O4
Mol. Mass.:
355.3877
SMILES:
COc1ccc(cc1N)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1
Structure:
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