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TargetPhosphoglycerate kinase 1
LigandBDBM50216695
Substrate/Competitorn/a
Meas. Tech.ChEMBL_371
IC50 8350±n/a nM
Citation Caplan, NAPogson, CIHayes, DJBlackburn, GM Novel bisphosphonate inhibitors of phosphoglycerate kinase. Bioorg Med Chem Lett8:515-20 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Phosphoglycerate kinase 1
Name:Phosphoglycerate kinase 1
Synonyms:Cell migration-inducing gene 10 protein | PGK1 | PGKA | PRP 2 | Phosphoglycerate kinase 1 | Primer recognition protein 2
Type:PROTEIN
Mol. Mass.:44619.74
Organism:Homo sapiens
Description:ChEMBL_104832
Residue:417
Sequence:
MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL
MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE
NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN
LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM
AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ
ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV
KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI
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  Blast E-value cutoff:
BDBM50216695
NameBDBM50216695
Synonyms:CHEMBL149058
TypeSmall organic molecule
Emp. Form.C8H11FO6P2
Mol. Mass.284.1153
SMILESOP(O)(=O)Cc1cccc(c1)C(F)P(O)(O)=O
Structure
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