Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50216893
Substrate
n/a
Meas. Tech.
ChEMBL_58783 (CHEMBL666970)
Ki
2.5±n/a nM
Citation
 Dubuffet, T; Newman-Tancredi, A; Cussac, D; Audinot, V; Loutz, A; Millan, MJ; Lavielle, G Novel benzopyrano[3,4-c]pyrrole derivatives as potent and selective dopamine D3 receptor antagonist. Bioorg Med Chem Lett 9:2059-64 (1999) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50216893
Synonyms:
CHEMBL293159
Type:
Small organic molecule
Emp. Form.:
C19H18N2O
Mol. Mass.:
290.359
SMILES:
[H][C@]12CN(Cc3ccccc3)C[C@]1([H])c1cc(ccc1OC2)C#N
Structure:
Search PDB for entries with ligand similarity: