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Target
Transglycosylase
Ligand
BDBM50217265
Substrate
n/a
Meas. Tech.
ChEBML_153093
IC50
1260±n/a nM
Citation
 Greenlee, ML; Laub, JB; Rouen, GP; DiNinno, F; Hammond, ML; Huber, JL; Sundelof, JG; Hammond, GG Dicationic 2-fluorenonylcarbapenems: potent anti-MRS agents with improved solubility and pharmacokinetic properties. Bioorg Med Chem Lett 9:3225-30 (1999) [PubMed]  Article 
Target
Name:
Transglycosylase
Synonyms:
B9Z08_11275 | EP54_02360 | EQ90_10185 | HMPREF3211_02644 | PBP2 | Penicillin binding protein 2 | Transglycosylase
Type:
PROTEIN
Mol. Mass.:
80439.51
Organism:
Staphylococcus aureus
Description:
ChEMBL_103873
Residue:
727
Sequence:
MTENKGSSQPKKNGNNGGKSNSKKNRNVKRTIIKIIGFMIIAFFVVLLLGILLFAYYAWKAPAFTEAKLQDPIPAKIYDKNGELVKTLDNGQRHEHVNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPKAAEDRKNTVLYLMHYHKRITDKQWEDAKKIDLKANLVNRTPEERQNIDTNQDSEYNSYVNFVKSELMNNKAFKDENLGNVLQSGIKIYTNMDKDVQKTLQNDVDNGSFYKNKDQQVGATILDSKTGGLVAISGGRDFKDVVNRNQATDPHPTGSSLKPFLAYGPAIENMKWATNHAIQDESSYQVDGSTFRNYDTKSHGTVSIYDALRQSFNIPALKAWQSVKQNAGNDAPKKFAAKLGLNYEGDIGPSEVLGGSASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETIEYDHTSHKAMSDYTAYMLAEMLKGTFKPYGSAYGHGVSGVNMGAKTGTGTYGAETYSQYNLPDNAAKDVWINGFTPQYTMSVWMGFSKVKQYGENSFVGHSQQEYPQFLYENVMSKISSRDGEDFKRPSSVSGSIPSINVSGSQDNNTTNRSTHGGSDTSANSSGTAQSNNNTRSQQSRNSGGLTGIFN
  
Inhibitor
Name:
BDBM50217265
Synonyms:
CHEMBL1626936
Type:
Small organic molecule
Emp. Form.:
C32H37Cl2N3O6
Mol. Mass.:
630.559
SMILES:
n/a
Structure:
Search PDB for entries with ligand similarity: