Reaction Details Report a problem with these data
Target
Isoleucyl-tRNA synthetase
Ligand
BDBM50217838
Substrate
n/a
Meas. Tech.
ChEMBL_88825 (CHEMBL698880)
IC50
<1730±n/a nM
Citation
 Shimizu, T; Usui, T; Machida, K; Furuya, K; Osada, H; Nakata, T Chemical modification of reveromycin A and its biological activities. Bioorg Med Chem Lett 12:3363-6 (2002) [PubMed]  Article 
Target
Name:
Isoleucyl-tRNA synthetase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
5742.00
Organism:
Rattus norvegicus
Description:
ChEMBL_88824
Residue:
50
Sequence:
MQTSLGNFVTTTGISSTRTPRPRRESVYFDLIKLKIFHQITQENPGSRNI
  
Inhibitor
Name:
BDBM50217838
Synonyms:
CHEMBL115939
Type:
Small organic molecule
Emp. Form.:
C33H50O8
Mol. Mass.:
574.7453
SMILES:
[H][C@]1(C\C=C(/C)\C=C\[C@H](O)[C@@H](C)\C=C\C(O)=O)O[C@@]2(CC[C@@](CCCC)(O2)[C@@H](OC)\C=C\C(\C)=C\C(O)=O)CC[C@@H]1C
Structure:
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