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Target
Alcohol dehydrogenase E/S chain
Ligand
BDBM50224829
Substrate
n/a
Meas. Tech.
ChEMBL_30849 (CHEMBL643567)
Ki
1100000±n/a nM
Citation
 Chadha, VK; Leidal, KG; Plapp, BV Inhibition by carboxamides and sulfoxides of liver alcohol dehydrogenase and ethanol metabolism. J Med Chem 26:916-22 (1983) [PubMed]  Article 
Target
Name:
Alcohol dehydrogenase E/S chain
Synonyms:
Alcohol dehydrogenase
Type:
n/a
Mol. Mass.:
n/a
Description:
ASSAY_ID of ChEMBL is 30849
Components:
This complex has 2 components.
Component 1
Name:
Alcohol dehydrogenase E chain
Synonyms:
1.1.1.1 | ADH1E_HORSE | Alcohol dehydrogenase E chain
Type:
PROTEIN
Mol. Mass.:
39942.66
Organism:
Equus caballus
Description:
ChEMBL_105061
Residue:
375
Sequence:
MSTAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF
  
Component 2
Name:
Alcohol dehydrogenase S chain
Synonyms:
1.1.1.1 | ADH1S_HORSE | Alcohol dehydrogenase S chain
Type:
PROTEIN
Mol. Mass.:
39633.49
Organism:
Equus caballus
Description:
ChEMBL_105061
Residue:
374
Sequence:
MSTAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVAPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKNLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGKSIRTILTF
  
Inhibitor
Name:
BDBM50224829
Synonyms:
CHEMBL174477 | Ethanesulfinyl-Ethane
Type:
Small organic molecule
Emp. Form.:
C4H10OS
Mol. Mass.:
106.187
SMILES:
CC[S+]([O-])CC
Structure:
Search PDB for entries with ligand similarity: