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Target
Beta-1 adrenergic receptor
Ligand
BDBM50225514
Substrate
n/a
Meas. Tech.
ChEMBL_38575 (CHEMBL652077)
Kd
10000±n/a nM
Comments
0.000010 20220115
Citation
 Reitz, AB; Sonveaux, E; Rosenkranz, RP; Verlander, MS; Melmon, KL; Hoffman, BB; Akita, Y; Castagnoli, N; Goodman, M Conjugates of catecholamines. 5. Synthesis and beta-adrenergic activity of N-(aminoalkyl)norepinephrine derivatives. J Med Chem 28:634-42 (1985) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1_MOUSE | Adrb1 | Adrb1r | Beta-1 adrenergic recepto | Beta-1 adrenergic receptor | Beta-1 adrenoceptor | Beta-1 adrenoreceptor
Type:
PROTEIN
Mol. Mass.:
50507.75
Organism:
Mus musculus
Description:
ChEMBL_105090
Residue:
466
Sequence:
MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAGMGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARALVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPEPSPSPGPPRPADSLANGRSSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDDDDDAGTTPPARLLEPWTGCNGGTTTVDSDSSLDEPGRQGFSSESKV
  
Inhibitor
Name:
BDBM50225514
Synonyms:
CHEMBL160277
Type:
Small organic molecule
Emp. Form.:
C14H24N2O3
Mol. Mass.:
268.352
SMILES:
CC(CCCCN)NCC(O)c1ccc(O)c(O)c1
Structure:
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