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TargetThymidine kinase
LigandBDBM50229850
Substrate/Competitorn/a
Meas. Tech.ChEMBL_208028
IC50 603±n/a nM
Citation Gambino, JFocher, FHildebrand, CMaga, GNoonan, TSpadari, SWright, G Quantitative structure-activity relationships of N2-phenylguanines as inhibitors of herpes simplex virus thymidine kinases. J Med Chem35:2979-83 (1992) [PubMed]  Article
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Thymidine kinase
Name:Thymidine kinase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:40396.73
Organism:Human herpesvirus 2
Description:ChEMBL_474155
Residue:376
Sequence:
MASHAGQQHAPAFGQAARASGPTDGRAASRPSHRQGASGARGDPELPTLLRVYIDGPHGV
GKTTTSAQLMEALGPRDNIVYVPEPMTYWQVLGASETLTNIYNTQHRLDRGEISAGEAAV
VMTSAQITMSTPYAATDAVLAPHIGGEAVGPQAPPPALTLVFDRHPIASLLCYPAARYLM
GSMTPQAVLAFVALMPPTAPGTNLVLGVLPEAEHADRLARRQRPGERLDLAMLSAIRRVY
DLLANTVRYLQRGGRWREDWGRLTGVAAATPRPDPEDGAGSLPRIEDTLFALFRVPELLA
PNGDLYHIFAWVLDVLADRLLPMHLFVLDYDQSPVGCRDALLRLTAGMIPTRVTTAGSIA
EIRDLARTFAREVGGV
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BDBM50229850
NameBDBM50229850
Synonyms:CHEMBL406300
TypeSmall organic molecule
Emp. Form.C11H8BrN5O
Mol. Mass.306.118
SMILESOc1[nH]c(Nc2cccc(Br)c2)nc2ncnc12
Structure
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n/a