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TargetMuscarinic acetylcholine receptor M2 and M4
LigandBDBM50006243
Substrate/Competitorn/a
Meas. Tech.ChEMBL_139224
Kd 19953±n/a nM
Citation Bravo, PResnati, GAngeli, PFrigerio, MViani, FArnone, AMarucci, GCantalamessa, F Synthesis and pharmacological evaluation of enantiomerically pure 4-deoxy-4-fluoromuscarines. J Med Chem35:3102-10 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Muscarinic acetylcholine receptor M2 and M4
Name:Muscarinic acetylcholine receptor M2 and M5
Synonyms:CHRM2 | Cholinergic, muscarinic M2 | RecName: Full=Muscarinic acetylcholine receptor M2
Type:GPCR
Mol. Mass.:51730.61
Organism:Homo sapiens (Human)
Description:P08172
Residue:466
Sequence:
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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  Blast E-value cutoff:
BDBM50006243
NameBDBM50006243
Synonyms:((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-trimethyl-ammonium | (4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-trimethyl-ammonium; iodide | CHEMBL12587 | CHEMBL292911
TypeSmall organic molecule
Emp. Form.C9H20NO2
Mol. Mass.174.2601
SMILESC[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a