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TargetCarbonic anhydrase 6
LigandBDBM50230221
Substrate/Competitorn/a
Meas. Tech.ChEMBL_47171
IC50 69±n/a nM
Citation Lo, YSNolan, JCMaren, THWelstead, WJGripshover, DFShamblee, DA Synthesis and physicochemical properties of sulfamate derivatives as topical antiglaucoma agents. J Med Chem35:4790-4 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 6
Name:Carbonic anhydrase 6
Synonyms:CA-VI | CA6 | Carbonate dehydratase VI | Carbonic anhydrase 6 | Carbonic anhydrase VI | Salivary carbonic anhydrase | Secreted carbonic anhydrase
Type:PROTEIN
Mol. Mass.:37008.14
Organism:Bos taurus
Description:ChEMBL_104851
Residue:319
Sequence:
MITLLFLLVVGAQAQHEWTYSEGVLDEKHWRLQYPDCGGTRQSPIDLKMKKVRYNPSLRA
LNLTGYGLRQGEFPMTNNGHTVQISLPSSMRMTTSDGSQYLAKQMHFHWGGDSSEISGSE
HTVDGMRYIIEIHVVHYHSKYGSYEEAQNEPDGLAVLAALVEVKDYAENTYYSNFISHLE
DIRYAGQSTVLRDLDIQDMLPGDLRYYYSYLGSLTTPSCTENVHWFVVADTVKLSKTQIE
KLENSLLNHQNETIQNNYRSTQPLNHRVVEANFVSHPHQEYTLGSKLHFYLNNIDQNLEY
LRRFIEQKITKRKKEKYWP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50230221
NameBDBM50230221
Synonyms:CHEMBL541599
TypeSmall organic molecule
Emp. Form.C11H14ClN3O4S
Mol. Mass.319.765
SMILESCl.NS(=O)(=O)OCCOc1cccc(c1)-n1ccnc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a