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Target
G-protein coupled receptor 35
Ligand
BDBM50233948
Substrate
n/a
Meas. Tech.
ChEMBL_1651788 (CHEMBL4001043)
IC50
>30000±n/a nM
Citation
 Abdalhameed, MM; Zhao, P; Hurst, DP; Reggio, PH; Abood, ME; Croatt, MP Structure-activity relationships of benzothiazole GPR35 antagonists. Bioorg Med Chem Lett 27:612-615 (2017) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM50233948
Synonyms:
CHEMBL4098795
Type:
Small organic molecule
Emp. Form.:
C26H22ClN3O4S2
Mol. Mass.:
540.054
SMILES:
[O-][S@@+](Cc1ccc(Cl)cc1)c1nc2ccc(NC(=O)c3ccccc3C(=O)N3CCOCC3)cc2s1 |r|
Structure:
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