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TargetRetinal dehydrogenase 2
LigandBDBM50236904
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1659727
IC50 1600±n/a nM
Citation Buchman, CDHurley, TD Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives. J Med Chem60:2439-2455 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Retinal dehydrogenase 2
Name:Retinal dehydrogenase 2
Synonyms:ALDH1A2 | Aldehyde dehydrogenase family 1 member A2 | RALDH 2 | RALDH(II) | RALDH2 | RalDH2 | Retinal dehydrogenase 2 | Retinaldehyde-specific dehydrogenase type 2
Type:PROTEIN
Mol. Mass.:56720.77
Organism:Homo sapiens (Human)
Description:ChEMBL_109700
Residue:518
Sequence:
MTSSKIEMPGEVKADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNP
ATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVL
ATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVC
GQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILP
GYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADAD
LDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQG
PQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFG
PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQ
SPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50236904
NameBDBM50236904
Synonyms:CHEMBL1335126
TypeSmall organic molecule
Emp. Form.C22H25NO4
Mol. Mass.367.4382
SMILESCc1oc2cc3oc(=O)c(CCC(=O)N4CCCCC4)c(C)c3cc2c1C
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a