Reaction Details Report a problem with these data
Target
Probable G-protein coupled receptor 34
Ligand
BDBM50238940
Substrate
n/a
Meas. Tech.
ChEMBL_1664557 (CHEMBL4014238)
EC50
27±n/a nM
Citation
 Sayama, M; Sayama, M; Sayama, M; Inoue, A; Inoue, A; Inoue, A; Nakamura, S; Nakamura, S; Nakamura, S; Jung, S; Jung, S; Jung, S; Ikubo, M; Ikubo, M; Ikubo, M; Otani, Y; Otani, Y; Otani, Y; Uwamizu, A; Uwamizu, A; Uwamizu, A; Kishi, T; Kishi, T; Kishi, T; Makide, K; Makide, K; Makide, K; Aoki, J; Aoki, J; Aoki, J; Hirokawa, T; Hirokawa, T; Hirokawa, T; Ohwada, T; Ohwada, T; Ohwada, T Probing the Hydrophobic Binding Pocket of G-Protein-Coupled Lysophosphatidylserine Receptor GPR34/LPS J Med Chem 60:6384-6399 (2017) [PubMed]  Article 
Target
Name:
Probable G-protein coupled receptor 34
Synonyms:
GPR34 | GPR34_HUMAN | Probable G-protein coupled receptor 34
Type:
PROTEIN
Mol. Mass.:
43892.32
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109761
Residue:
381
Sequence:
MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFKPGYSLHDTSVAVKIQSSSKST
  
Inhibitor
Name:
BDBM50238940
Synonyms:
CHEMBL4096239
Type:
Small organic molecule
Emp. Form.:
C29H34NO10P
Mol. Mass.:
587.5547
SMILES:
Cc1ccc(Oc2cccc(COc3ccccc3CCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O)c2)cc1 |r|
Structure:
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