Reaction Details Report a problem with these data
Target
Glycine amidinotransferase, mitochondrial
Ligand
BDBM22913
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2292
Citation
 Leurs, R; Tulp, MT; Menge, WM; Adolfs, MJ; Zuiderveld, OP; Timmerman, H Evaluation of the receptor selectivity of the H3 receptor antagonists, iodophenpropit and thioperamide: an interaction with the 5-HT3 receptor revealed. Br J Pharmacol 116:2315-21 (1995) [PubMed]  Article 
Target
Name:
Glycine amidinotransferase, mitochondrial
Synonyms:
Agat | GATM_RAT | Gatm | Glycine | Glycine amidinotransferase, mitochondrial
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48247.66
Organism:
RAT
Description:
Glycine 0 RAT::P50442
Residue:
423
Sequence:
MLRVRCLRGGSRGAEAVHYIGSRLGGSLTGWVQRTFQSTQAATASSQNSCAAEDKATHPLPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQKNGGLYFPKDHLKKAVAEVEEMCNILSMEGVTVKRPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGLVLSNPDRPCHQIDLFKKAGWTIVTPPTPVIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGISTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYFD
  
Inhibitor
Name:
BDBM22913
Synonyms:
CHEMBL1237146 | CHEMBL498770 | Iodophenpropit | {[3-(1H-imidazol-5-yl)propyl]sulfanyl}-N''-[2-(4-iodophenyl)ethyl]methanimidamide
Type:
Small organic molecule
Emp. Form.:
C15H19IN4S
Mol. Mass.:
414.308
SMILES:
NC(SCCCc1cnc[nH]1)=NCCc1ccc(I)cc1 |w:11.12|
Structure:
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