Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 7
Ligand
BDBM85032
Substrate
n/a
Ki
35±n/a nM
Comments
PDSP_842
Citation
 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berl) 124:57-73 (1996) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-hydroxytryptamine receptor 7 | 5-hydroxytryptamine receptor 7 (5HT7) | 5HT7 | 5HT7R_MOUSE | Htr7 | Serotonin 7 (5-HT7) receptor
Type:
Enzyme
Mol. Mass.:
49932.71
Organism:
Mus musculus (Mouse)
Description:
P32304
Residue:
448
Sequence:
MMDVNSSGRPDLYGHLRSLILPEVGRRLQDLSPDGGAHSVVSSWMPHLLSGFPEVTASPAPTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFSGFPRVQPESVISLNGVVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERSEFVLQNCDHCGKKGHDT
  
Inhibitor
Name:
BDBM85032
Synonyms:
CAS_54965-22-9 | FLUSPIPERONE | NSC_166535
Type:
Small organic molecule
Emp. Form.:
C23H25F2N3O2
Mol. Mass.:
413.4603
SMILES:
Fc1ccc(cc1)N1CNC(=O)C11CCN(CCCC(=O)c2ccc(F)cc2)CC1
Structure:
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