Reaction Details Report a problem with these data
Target
Melatonin receptor
Ligand
BDBM29611
Substrate
n/a
Ki
0.27±n/a nM
Comments
PDSP_1192
Citation
 Dubocovich, ML; Masana, MI; Iacob, S; Sauri, DM Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol 355:365-75 (1997) [PubMed]  Article 
Target
Name:
Melatonin receptor
Synonyms:
Melatonin | Melatonin receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
13287.02
Organism:
RABBIT
Description:
Q9BE38
Residue:
114
Sequence:
MIWMLTLVAVMPNLHTGTLQYDPRVYSCTFSQSVSSAYTIAVVVFHFIIPMLMSSCCYLRIWILVLQVRRRVKPDNKPKLKPQDFRNFITMFVVFVLFAICWAPLNFIVLLGRS
  
Inhibitor
Name:
BDBM29611
Synonyms:
2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo
Type:
Small organic molecule
Emp. Form.:
C13H15IN2O2
Mol. Mass.:
358.1749
SMILES:
COc1ccc2[nH]c(I)c(CCNC(C)=O)c2c1
Structure:
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