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TargetMetabotropic glutamate receptor 6
LigandBDBM17664
Substrate/Competitorn/a
Ki 2700±n/a nM
CommentsPDSP_3212
Citation Conn, PJPin, JP Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharmacol Toxicol37:205-37 (1997) [PubMed]  Article
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Metabotropic glutamate receptor 6
Name:Metabotropic glutamate receptor 6
Synonyms:GRM6 | Metabotropic glutamate receptor 6 | glutamate receptor, metabotropic 6 precursor | mGluR6 | metabotropic glutamate 6
Type:Enzyme Catalytic Domain
Mol. Mass.:95479.26
Organism:Homo sapiens (Human)
Description:metabotropic glutamate 6 GRM6 HUMAN::O15303
Residue:877
Sequence:
MARPRRAREPLLVALLPLAWLAQAGLARAAGSVRLAGGLTLGGLFPVHARGAAGRACGQL
KKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGR
GDGDEVGVRCPGGVPPLRPAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPE
LSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREA
GGVCIAQSIKIPREPKPGEFSKVIRRLMETPNARGIIIFANEDDIRRVLEAARQANLTGH
FLWVGSDSWGAKTSPILSLEDVAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEF
WEENFNCKLTSSGTQSDDSTRKCTGEERIGRDSTYEQEGKVQFVIDAVYAIAHALHSMHQ
ALCPGHTGLCPAMEPTDGRMLLQYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNG
SASSGGYQAVGQWAETLRLDVEALQWSGDPHEVPSSLCSLPCGPGERKKMVKGVPCCWHC
EACDGYRFQVDEFTCEACPGDMRPTPNHTGCRPTPVVRLSWSSPWAAPPLLLAVLGIVAT
TTVVATFVRYNNTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPGAAVCAARRLFLGLG
TTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFSLTSLQVVGMIAWLGARP
PHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFN
EAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKT
YVILFHPEQNVQKRKRSLKATSTVAAPPKGEDAEAHK
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  Blast E-value cutoff:
BDBM17664
NameBDBM17664
Synonyms:(2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEMBL284377 | L-SOP | L-serine O-phosphate
TypeSmall organic molecule
Emp. Form.C3H8NO6P
Mol. Mass.185.0725
SMILESN[C@@H](COP(O)(O)=O)C(O)=O
Structure
n/a