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TargetHTR2A
LigandBDBM82517
Substrate/Competitorn/a
Ki 219±n/a nM
CommentsPDSP_1289
Citation Mos, JVan Hest, AVan Drimmelen, MHerremans, AHOlivier, B The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. Eur J Pharmacol325:145-53 (1997) [PubMed]
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HTR2A
Name:HTR2A
Synonyms:5-HT2A
Type:Enzyme Catalytic Domain
Mol. Mass.:105583.25
Organism:pigeon
Description:5-HT2A HTR2A pigeon::A0A1V4J4E5
Residue:946
Sequence:
MGVFVKDSSDSAYLTPERKLALGRGKAQGKSRQAAYLSEEKNKPRSTGTGFTQVCSLEVK
KLFQIPPFWRRLKKRDAKLAKHNEEYSESVQSEPNRILRVGSDVQPGFSMYAYTGLPMEL
KTKHFSIQSNSVSNFAMDILCDQESSVNPTAKSLIQINHERRLYRNVYGAGEINASHLFN
LTVDSENLTNVSSESSVTPPCYSSLFQLSQKNWPALLTVIVIVLTIAGNILVIMAVSLEK
KLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYAWPLPRKLCAIWIYLDVLFSTASI
MHLCAISLDRYIAIRNPIHHSRFNSRTKAFAKIIAVWTISVGISMPVPVFGLQDDSKVFK
KDSCLLADDNFVLVGSFVAFFIPLTIMVVTYFLTIKSLQKEAMLCVNDIGPKTKFASFSF
LPQSSLSSEKLFQRSLNRDVGTSGRRTMQSISNEQKASKVLGIVFFLFVVMWCPFFITNV
MAVICKESCNQEVIGELLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCRYKEEKK
PFQLILVNTIPALAYNSSQLQLAQMKSLKKEAKMMAKDYSMVTIGIHHLDGTSKGSISPV
NENVSETAAQHPPWQTQTGRLRALPRSAGGPGRQAGRLEAAPARGQPPPPVLRRAAPPLL
LVKAMALKQVSSNKCFEGFQKVFEHDSAELKCKMKFGIYLPPKAETGKCPVLYWLSGLTC
TEQNFITKAGFHQAAAEHGLIVVAPDTSPRGCNIEGEDESWDFGTGAGFYVDATEDPWKT
NYRMYSYIKDELPKLINANFPTDPERMSIFGHSMGGHGALILALKNPGKYKSVSAFAPIC
NPMQCQWGKKALGGYLGSDASKWEAYDATQLVKSYPDSHLDILIDQGKDDQFLSAGQLLP
DNFIAACTERKIPVVFRLQQGYDHSYFFIATFINDHIKHHAKYLNA
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  Blast E-value cutoff:
BDBM82517
NameBDBM82517
Synonyms:2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione | CAS_107966 | CHEMBL126632 | CHEMBL8618 | NAN-190 | NSC_107966
TypeSmall organic molecule
Emp. Form.C23H27N3O3
Mol. Mass.393.4788
SMILESCOc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a