Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetHTR2A
LigandBDBM50019443
Substrate/Competitorn/a
Ki>10000±n/a nM
CommentsPDSP_1495
Citation Mos, JVan Hest, AVan Drimmelen, MHerremans, AHOlivier, B The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. Eur J Pharmacol325:145-53 (1997) [PubMed]
More Info.:Get all data from this article
 
HTR2A
Name:HTR2A
Synonyms:5-HT2A
Type:Enzyme Catalytic Domain
Mol. Mass.:105583.25
Organism:pigeon
Description:5-HT2A HTR2A pigeon::A0A1V4J4E5
Residue:946
Sequence:
MGVFVKDSSDSAYLTPERKLALGRGKAQGKSRQAAYLSEEKNKPRSTGTGFTQVCSLEVK
KLFQIPPFWRRLKKRDAKLAKHNEEYSESVQSEPNRILRVGSDVQPGFSMYAYTGLPMEL
KTKHFSIQSNSVSNFAMDILCDQESSVNPTAKSLIQINHERRLYRNVYGAGEINASHLFN
LTVDSENLTNVSSESSVTPPCYSSLFQLSQKNWPALLTVIVIVLTIAGNILVIMAVSLEK
KLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYAWPLPRKLCAIWIYLDVLFSTASI
MHLCAISLDRYIAIRNPIHHSRFNSRTKAFAKIIAVWTISVGISMPVPVFGLQDDSKVFK
KDSCLLADDNFVLVGSFVAFFIPLTIMVVTYFLTIKSLQKEAMLCVNDIGPKTKFASFSF
LPQSSLSSEKLFQRSLNRDVGTSGRRTMQSISNEQKASKVLGIVFFLFVVMWCPFFITNV
MAVICKESCNQEVIGELLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCRYKEEKK
PFQLILVNTIPALAYNSSQLQLAQMKSLKKEAKMMAKDYSMVTIGIHHLDGTSKGSISPV
NENVSETAAQHPPWQTQTGRLRALPRSAGGPGRQAGRLEAAPARGQPPPPVLRRAAPPLL
LVKAMALKQVSSNKCFEGFQKVFEHDSAELKCKMKFGIYLPPKAETGKCPVLYWLSGLTC
TEQNFITKAGFHQAAAEHGLIVVAPDTSPRGCNIEGEDESWDFGTGAGFYVDATEDPWKT
NYRMYSYIKDELPKLINANFPTDPERMSIFGHSMGGHGALILALKNPGKYKSVSAFAPIC
NPMQCQWGKKALGGYLGSDASKWEAYDATQLVKSYPDSHLDILIDQGKDDQFLSAGQLLP
DNFIAACTERKIPVVFRLQQGYDHSYFFIATFINDHIKHHAKYLNA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50019443
NameBDBM50019443
Synonyms:1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol | 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol((-)-Pindolol) | 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol(pindolol) | 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol | LB-46 | PINDOLOL | PINDOLOL,(-) | PRINODOLOL | VISKAZIDE | VISKEN
TypeSmall organic molecule
Emp. Form.C14H20N2O2
Mol. Mass.248.3208
SMILESCC(C)NCC(O)COc1cccc2[nH]ccc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a